Lung Abnormalities Identified on Hp-XeMRI in Long Outpatient COVID Patients – Consumer Health News


THURSDAY, June 2, 2022 (HealthDay News) — Specialized imaging shows post-hospitalized COVID-19 patients (PHC) and non-hospitalized patients with post-COVID-19 disease (NHLC) have lung abnormalities, according to a study published online May 24 in Radiology.

James T. Grist, Ph.D., of Oxford University Hospitals NHS Trust in the UK, and colleagues examined whether previously described lung abnormalities on hyperpolarized 129Magnetic resonance imaging (MRI) of xenon (Hp-Xe) in PHCs was present in participants with NHLC. Data were included from 11 NHLC patients and 12 PHC patients, who were approximately 287 and 143 days from infection, respectively.

Researchers found normal or nearly normal CT scans for NHLC and PHC participants. Gas transfer differed between groups (76% for NHLC and 86% for PHC), but no further evidence of differences in lung function was observed. Compared to healthy volunteers, both PHCs and NHLCs had a significantly lower mean red blood cell:tissue plasma, but no difference was observed between NHLCs and PHCs participants. No correlation was observed for large-scale airway network modeling with Hp-XeMRI or gas transfer.

“We saw that the ability of gas to transfer from the lungs into the bloodstream was less in non-hospitalized patients compared to those hospitalized with COVID,” a co-author said in a statement. “Furthermore, both groups of participants had lower dissolved phase Hp-XeMRI values ​​than healthy participants, indicating potential defects in the lining of the lungs or surrounding blood vessels.”

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